An Efficient Synthesis of Pyrethroid Insecticides Containing Spiro-fused Cyclopropane Carboxylate

Abstract

Among the active pyrethroid insecticides containing various substituted cyclpropanecarboxylates, esters derived from 2,2-dimethyl-5,6-benzospiro [2,4] heptene-1-carboxylic acid (1) have been 1 found to have particularly high activity, Our continuing interest in the synthesis of novel pyrethroid insecticides2 led us to a study of synthetic methodology for constructing spiro-fused systems such as (1).