The AlCL₃ Catalyzed Benzoylation of Ethyl Pyrrole-2-Acetate: An Unusual 6-Substitution

Abstract

In this study, synthetic methodologies have been developed which are potentially useful in preparing 4- and 5-aroylpyrrole-2-acetic acids bearing no alkyl substituents on the heterocyclic nitrogen. These compounds are structurally related to a class of NSAIDs.