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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 26, 1996 - Issue 14
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Original Articles

An Efficient Process for the Synthesis of Renin Inhibitor, ABT-517

Pulla Reddy Singam Process Research and Development, D54P Abbott Laboratories, N. Chicago, Illinois, 60064
,
Curt W. Bradshaw Process Research and Development, D54P Abbott Laboratories, N. Chicago, Illinois, 60064
,
Jerome A. Menzia Process Research and Development, D54P Abbott Laboratories, N. Chicago, Illinois, 60064
,
B. A. Narayanan Process Research and Development, D54P Abbott Laboratories, N. Chicago, Illinois, 60064
,
Todd W. Rockway Process Research and Development, D54P Abbott Laboratories, N. Chicago, Illinois, 60064
,
Noel Welch Process Research and Development, D54P Abbott Laboratories, N. Chicago, Illinois, 60064
&
Jien-Heh J. Tien Process Research and Development, D54P Abbott Laboratories, N. Chicago, Illinois, 60064
 show all
Pages 2751-2756 | Received 02 Feb 1996, Published online: 21 Aug 2006
 
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Abstract

An efficient process for the preparation of renin inhibitor, ABT-517 is described. The process avoids solvent extractions or chromatographic purifications and is used on multi-kilogram scale.

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