Synthesis of Bicyclo[3.2.1]-octanone Derivatives by Metal Catalyzed Decomposition of α-Diazomethylketones

Abstract

Highly functionalized bicyclo[3.2.1]-octanone derivatives have been prepared by metal catalyzed decompostion of diazoketones through a net retention of configuration at the benzylic center.

Present Address: University of Texas, M.D. Anderson Cancer Center, Department of Molecular Pathology-89, 1515 Holcolmbe Blvd., Houston, TX 77030, USA

Notes

Present Address: University of Texas, M.D. Anderson Cancer Center, Department of Molecular Pathology-89, 1515 Holcolmbe Blvd., Houston, TX 77030, USA