Facile and Effective Synthesis of N-Aryl-2-Furancarboxamides Derivatives Under the Condition of Phase Transfer Catalysis

Abstract

A convenient one-pot procedure is reported for the preparation of N-aryl-2-furancarboxamide derivatives. 2-Furoic acid is activated by benzenesuifonyl chloride under the condition of solid-liquid phase transfer catalysis using solid potassium carbonate as base and polyethylene glycol-400-(PEG-400) as phase transfer catalyst.