Abstract
Synthesis of 2-memyl-8-phenyl-5) 6,7,8,10,11-hexahydrobenzo[6,7]-cyclohepta[d][1,3]thiazolo[3,2-a]pyrimidin-10-ones (4a-g), 2-methyl-8-phenyl-5,6,7,8,11,12-hexahydro-10H-bemzo[6′,7′]cyclohepta[4,5]pyrimido[2,1-b][1,3]-thiazin-10-ones (6a-g) and 2,11-dimethyl-8-phenyl-5,6,7,8,10,11-hexahydro-benzo[6,7]cyclohepta[d][1,3]thiazolo[3,2-a]pyrimidin-10-ones (8a-g) have been described. A number of compounds show promising antimicrobial acitity.