Diffusion of jojoba oil microencapsulated and impregnated onto compressive garment through a pig skin

Abstract

Scientific developments are in progress in order to create compressive fabric in the medical field. This study focused on the development of a compressive garment in polyamide designated for severe burns in terms of pressure and hydration release. The fabric was then enhanced by adding a moisturizing treatment. The improvement consisted of the impregnation of ethylcellulose microcapsules containing jojoba oil on the textile surface of compressive garment. The kinetic of release of this active ingredient from the microcapsules, as well as its diffusion through the skin, were assessed using the in vitro Franz diffusion cell system. The results showed a controlled release of jojoba oil over time. The amount of oil released during the experiments (168 h) and that which penetrated through the pig skin did not exceed 1% of the total amount of jojoba oil microencapsulated and impregnated on the surface of a compression garment. This study permitted to obtain a compressive garment which presents hydration properties.

Keywords:

• microcapsules
• jojoba oil
• hydration
• skin
• compressive garment

Notes

Jaâfar Fadhel and Lassoued Mohamed Ali contributed equally.