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Correspondence

Biochemical characterisation of caprine arthritis-encephalitis virus

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Abstract

Extract

Sir:– Recently, caprine arthritis-encephalitis virus (CAEV) was isolated in New Zealand.(Citation5) The virus induced syncytial cell formation in cell culture, budded from the cytoplasmic membrane of infected cells, was 80-100 nm in diameter, and reacted with both CAEV- and maedi/visna-positive antisera. We wish to present evidence that this isolate of CAEV has other biochemical characteristics of the Retroviridae. The two biochemical techniques used were the detection of 3H uridine-Iabelled virus and the assay for viral RNA-directed DNA polymerase (RDDP).

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