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International Journal of Polymeric Materials and Polymeric Biomaterials Volume 64, 2015 - Issue 4
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Original Articles

Human Gingival Fibroblasts Cell Viability of Poly(Lactic Acid) Powder Reinforced PMMA/Hydroxyapatite Biocomposites

W. S. Chow School of Materials and Mineral Resources Engineering, Engineering Campus, Universiti Sains Malaysia, Nibong Tebal, Pulau Pinang, MalaysiaCorrespondence[email protected]
,
K. Ng School of Materials and Mineral Resources Engineering, Engineering Campus, Universiti Sains Malaysia, Nibong Tebal, Pulau Pinang, Malaysia
,
Z. A. Mohd Ishak School of Materials and Mineral Resources Engineering, Engineering Campus, Universiti Sains Malaysia, Nibong Tebal, Pulau Pinang, Malaysia
,
H. Hashim Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, Pulau Pinang, Malaysia
&
S. N. F. Mohd Noor Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, Pulau Pinang, Malaysia
Pages 192-197 | Received 03 Jan 2014, Accepted 26 May 2014, Published online: 27 Oct 2014
 
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Abstract

The dental composites based on poly(methyl methacrylate)/hydroxyapatite (PMMA/HA) were prepared through heat-processing polymer powder-liquid method, in the presence of poly(lactic acid) powder (PLA; 5–20 phr). The PLA powder enhanced the flexural modulus and strength of PMMA/HA composites. The Alamar Blue assay results indicated the PMMA/HA/PLA composites were able to sustain human gingival fibroblasts (HGF) cells growth. The images of live/dead cells confocal showed the populations of living cells on the composites surface were confluent and the survival of HGF cells on the PMMA composites surface are assured. These features suggested that the PLA powder reinforced PMMA/HA composites demonstrated excellent biocompatibility.

GRAPHICAL ABSTRACT

Notes

Color versions of one or more of the figures in the article can be found online at www.tandfonline.com/gpom.

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