Advanced search
Publication Cover
International Journal of Polymeric Materials and Polymeric Biomaterials Volume 66, 2017 - Issue 2
Submit an article Journal homepage
451
Views
18
CrossRef citations to date
0
Altmetric
Original Articles

Succinyl pullulan-crosslinked carboxymethyl chitosan sponges for potential wound dressing

Xin WangEngineering Research Center for Biomedical Materials, School of Life Science, Anhui University, Hefei, P. R. China
,
Di ZhangSchool of Pharmaceutical Science, Jiangnan University, Wuxi, P. R. China
,
Jun WangEngineering Research Center for Biomedical Materials, School of Life Science, Anhui University, Hefei, P. R. China
,
Rupei TangEngineering Research Center for Biomedical Materials, School of Life Science, Anhui University, Hefei, P. R. ChinaCorrespondence[email protected]
,
Bing WeiEngineering Research Center for Biomedical Materials, School of Life Science, Anhui University, Hefei, P. R. China
&
Qiong JiangEngineering Research Center for Biomedical Materials, School of Life Science, Anhui University, Hefei, P. R. China
Pages 61-70 | Received 03 Dec 2015, Accepted 22 Apr 2016, Published online: 11 May 2016
 
Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days

ABSTRACT

The crosslinked succinyl pullulan-carboxymethyl chitosan composite sponges (Pullulan-CMCS) were fabricated for potential wound dressing. The structure and micromorphology of Pullulan-CMCS sponges were investigated by FTIR spectroscopy and SEM. Pullulan-CMCS sponges had lots of porous structures, making it absorb much liquid and quickly reach swelling equilibrium. WVTR results showed that Pullulan-CMCS sponges can reduce the accumulation of wound exudates in a certain degree. Biocompatibility test showed these sponges had no cytotoxicity or hemolytic potential. In vivo experiments demonstrated that Pullulan-CMCS sponges can effectively heal full-layer wound of skin defects of male ICR mice with accelerated fibroblast proliferation and enhanced epithelial migration.

GRAPHICAL ABSTRACT

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 1,070.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.