Novel 3D electrospun polyamide scaffolds prepared by 3D printed collectors and their interaction with chondrocytes

ABSTRACT

Electrospinning is significantly one of the simple and versatile methods for producing micro- and nanofibrous scaffolds. Its assembly can be modified in different ways to combine material properties with different morphological structures for biomedical applications. In this process, collector design plays an important role to determine the nanofiber orientation in electrospun nanoweb. In this work, 3D patterned scaffolds were produced by electrospinning of polyamide-66 solution on different 3D collectors that have been obtained. The aim of this work is to investigate the attachment of the chondrocyte cells on the prepared electrospun scaffolds that have different types of nanofiber orientations that could be used in tissue engineering applications.

GRAPHICAL ABSTRACT

KEYWORDS:

• 3D printer
• cell culture
• chondrocytes
• electrospinning
• nanofibers
• patterned collectors
• polyamide-66 scaffold
• tissue engineering

Acknowledgments

This study was conducted in the frame of COST Action MP1206 electrospun nanofibers for bio inspired composite materials and innovative industrial applications.