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International Journal of Polymeric Materials and Polymeric Biomaterials Volume 69, 2020 - Issue 13
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Articles

Preparation of pesticide-loaded microcapsules by liquid-driven coaxial flow focusing for controlled release

Fengjing ZhongDepartment of Polymer Science and Engineering, University of Science and Technology of China, Hefei, China; View further author information
,
Chaoyu YangDepartment of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, China; View further author information
,
Qiang WuDepartment of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, China; View further author information
,
Shiyu WangDepartment of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, China; View further author information
,
Lei ChengHospital, University of Science and Technology of China, Hefei, China; View further author information
,
Pankaj DwivediDepartment of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, China; View further author information
,
Zhiqiang ZhuDepartment of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, China; Correspondence[email protected]
View further author information
,
Ting SiDepartment of Modern Mechanics, University of Science and Technology of China, Hefei, China; View further author information
&
Ronald X. XuDepartment of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, China; ;Department of Biomedical Engineering, The Ohio State University, Columbus, OH, USAView further author information
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Pages 840-847 | Received 22 Jan 2019, Accepted 08 May 2019, Published online: 08 Jun 2019
 
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Abstract

Microencapsulation of pesticide can reduce mammalian toxicity, phyto-toxicity, and protect the pesticides from rapid environmental degradation. The aim of this study was to develop a liquid-driven coaxial flow focusing (LDCFF) process for fabricating pesticide-loaded microcapsules having high encapsulation efficiency, loading efficiency and yield. We have optimized and evaluated the effects of process parameters on the size and morphology of pesticide-loaded microcapsules. The release of pesticides from pesticide-loaded microcapsules has sustained release profiles, which depends on their core-shell structure and shell material degradation process. LDCFF process enables successful encapsulation of pesticides in microcapsules with tunable characteristics important in pesticide applications.

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Additional information

Funding

This work was supported by National Natural Science Foundation of China [No. 11722222], the China Postdoctoral Science Foundation [2017M622014] and the Strategic Priority Research Program of the Chinese Academy of Sciences [No. XDB22040403].

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