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Articles

A new approach for the production of multifilament suture - in vitro and in vivo analysis

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Pages 1306-1315 | Received 04 Feb 2020, Accepted 16 Jul 2020, Published online: 30 Jul 2020
 

Abstract

We investigated, unique multifilament suture (UMS) was prepared from animal skin fiber (ASF) and cotton fiber (CF), which can be used for external surgeries and wound-healing applications. The distinctive properties of the UMS is that it shows tensile strength of 85.25 ± 0.09 (Mpa), 81.9 ± 0.46 (%) as elongation at break, 7.59 ± 0.26 (kgf) knot strength, 58.95 ± 0.55 (%) of flexibility and water absorption of about 51.03 ± 0.63 (%). In vitro study, performed its biocompatible in nature and in vivo experiments exhibited accelerated suturing and wound-healing properties.

Graphical Abstract

Disclosure statement

The authors of this manuscript have no conflicts of interest related to the content of the study.

Additional information

Funding

Dr. Senthil Rethinam (Project Investigator) acknowledges the funding support was granted by the National Postdoctoral Fellowship Scheme [Project No: PDF/2015/00063], Science and Engineering Research Board, Department of Science and Technology, Goverment of India. Currently, Dr. Senthil Rethinam (Project Coordinator) acknowledges the funding support granted by the 2232-International Fellowship for Outstanding Researcher Program of TUBITAK [Project No:118C350], Republic of Turkey.

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