Polysaccharide and protein-based functional wound dressing materials and applications

Abstract

In chronic wounds area, there is an abnormally low amount of extracellular matrix, which urges for the extra new biomimetic material to promote proper wound healing. Because of their unique characteristics such as inherent bioactivity, biocompatibility, biodegradability and mimicking the natural ECM, natural polymer and their derivative are widely explored as the functional active wound dressing and carrier of antimicrobial agents or growth factors to enhance wound healing. In this review, the wound healing application of polysaccharides, proteins and their derivatives as the active wound dressing and as the carriers of pharmaceutical agents was briefly reviewed.

Graphical Abstract

Keywords:

• Natural polymer
• polysaccharide dressing
• protein dressing
• wound hailing

Disclosure statement

The authors declare no conflict of interest.

Author contributions

Tilahun Ayane Debele, conceived, designed and wrote the review paper; Wen-Pin Su edited the review paper.

Additional information

Funding

The authors would like to thank the Ministry of Science and Technology, Taiwan [MOST 108-2811-B-006-501], [MOST 108-2811-B-006-525], [MOST 106-2314-B-006-074-MY3], [MOST 109-2314-B-006-078] and [MOST 109-2314-B-006-084] for financial support.