https://orcid.org/0000-0003-4262-739X
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Abstract
The risk of clot formation in blood-contacting devices is a significant concern. Therefore, development of biomaterials with improved hemocompatibility is a clinical need. Altering surface properties is an effective strategy to enhance the hemocompatibility. We have investigated the effect of hydrophilic polyethylene glycol (PEG) amount over the hydrophobic polycarbonate (PC) on hemocompatibility of polyurethanes. The presence of PEG on the surface was evaluated using ATR, AFM, and WCA. At above 20% of PEG to PC ratios, exhibit zero WCA, considerable improvement in hemocompatibility, was achieved. The results indicated the synthesized PUs could be used as coatings of cardiovascular devices.
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Funding
The authors gratefully acknowledge financial support from the Basque Government and the University of the Basque Country for funding this work through projects IT 1313-19 and GIU19/077. Technical and human support provided by Macro-behavior- Mesostructure Nanotechnology SGIker Service of UPV/EHU and Ms. Azar Najafi are also gratefully acknowledged.