New Cd(II) and Cu(II) coordination polymers: optical properties and therapeutic effect on gastric ulcer

Abstract

Two ternary coordination polymers of {(H₂bipy)[Cd(H₂L)(H₂O)₂)]}_n·2n(H₂O) (1) and [Cu₂(H₂L)₂(bpp)₂(H₂O)₂]_n·n(H₂O) (2) (H₄L = 4-(3,4-dicarboxyphenoxy)benzene-1,2-dicarboxylic acid, 4,4′-bipy = 4,4′-bipyridine, bpp = 1,3-bis(4-pyridyl)propane) were hydrothermally synthesized via the dual-ligand self-assembly strategy and structurally characterized. Luminescence measurement shows that the solids of 1 show intense luminescence at room temperature, and photocatalytic activity investigation indicated that the solids of 2 are photocatalytically active for the degradation of methyl violet (MV) under UV light irradiation. Furthermore, the therapeutic effect of the compound on gastric ulcers was evaluated in this research. The inflammatory cytokines released into the gastric secretion were measured with an ELISA assay. 

Graphical Abstract

Keywords:

• Coordination polymer
• gastric ulcer
• luminescence
• photocatalysis

Disclosure statement

No potential conflict of interest was reported by the author(s).

Data availability statement

Selected bond lengths (Å) and angles (°) for compounds 1–2 (Table S1); The hydrogen-bond parameters for compound 1 (Table S2); The luminescent emission spectra of compound 1 and free organic ligands at room temperature (Figure S1), the information could be found in the supporting information file.

Scheme 1. The chemical drawings of the ligands used in this work.