![Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/110819/TOC-Subject-Sample-2021-Physical-Sciences.jpg"})
Abstract
Factors affecting the drug release from biodegradable microparticles are reviewed. It is shown that spherical microparticles ranging in diameters from below 1μ to over 100μ along with the nanoparticles with the size less than 1000nm are particularly effective. The role of molecular weight, molecular weight distribution and co-polymer ratio and distribution is also discussed. Important drug parameters are the solubility of the drug in biological fluids and possible polymer particle-drug interactions. The role of microporosity may be essential in delivery of high molecular weight substances.
