Synthesis and Characterization of Biologically Active Oxovandium(V) and Manganese(II) Complexes of Semicarbazones

Abstract

Several new complexes of oxovandium(V) and manganese(II) with the monobasic bidentate ligands 2-acetylnaphthalene semicarbazone, 2-acetylthiophene semicarbazone, 2-acetylfuran semicarbazone and 2-acetylpyridine semicarbazone have been prepared and characterized by elemental analysis, magnetic moments, IR, ¹H NMR and electronic spectral studies. The complexes were monomeric and non-electrolytes. A probable tetracoordinated tetrahedral geometry for manganese complexes and a pentacoordinated distorted trigonal bipyramidal and hexacoordinated octahedral geometries for 1:1 and 1:2 (M:L) oxovanadium complexes, respectively, have been proposed. Some representative complexes of manganese and oxovanadium are found to have remarkable antifungal and antibacterial activities.