Abstract
A novel vic-dioxime ligand with a thiourea moiety, (4E,5E)-1,3-bis{4-[(4-bromophenylamino)methylene]phenyl}-2-thiooxaimidazoline-4,5-dione dioxime (4) (bmdH2) has been synthesized from N,N′-bis{4-[(4-bromophenylamino)methylene]phenyl}thiourea and (E,E)-dichloroglyoxime. The bmdH2 ligand (4) forms transition metal complexes [M(bmdH)2] with a metal : ligand ratio of 1 : 2 with M = Ni(II), Co(II), and Cu(II). The mononuclear Ni(II), Co(II) and Cu(II) complexes, [Ni(bmdH)2] (5), [Co(bmdH)2] (6) and [Cu(bmdH)2] (7) have the metal ions coordinated through the two N,N atoms, as do most vic-dioximes. Elemental analyses, molar conductivity, magnetic susceptibility, IR, 1H NMR spectra, and UV-Visible spectroscopy were used to elucidate the structures of the ligand and its complexes. Conductivity measurements have shown that the mononuclear complexes are non-electrolytes. In addition, the ligands and metal complexes were screened for antibacterial and antifungal activities by agar well diffusion techniques using DMF as solvent.