Polydentate Schiff-base ligands and their Cd(II) and Cu(II) metal complexes: synthesis, characterization, biological activity and electrochemical properties

Abstract

Synthesis, characterization, microbiological activity and electrochemical properties of the Schiff-base ligands A¹–A⁵ and their Cd(II) and Cu(II) metal complexes are reported. The ligands and their complexes have been characterized by elemental analysis, FT–IR, UV–Vis, ¹H- and ¹³C-NMR, mass spectra, magnetic susceptibility and conductance measurements. In the complexes, all the ligands are bidentate, the oxygen in the ortho position and azomethine nitrogen atoms of the ligands coordinate to the metal ions. The keto-enol tautomeric forms of the Schiff-base ligands A¹–A⁵ have been investigated in polar and non-polar organic solvents. Antimicrobial activity of the ligands and metal complexes were tested using the disc diffusion method and the chosen strains include Bacillus megaterium and Candida tropicalis. The electrochemical properties of the ligands A¹–A⁵ and their Cu(II) metal complexes have been investigated at different scan rates (100–500 mV s⁻¹) in DMSO.

Keywords:

• Schiff bases
• Antimicrobial activity
• Electrochemical properties

Acknowledgement

I wish to thank Dr Metin Dłğrak (K. Maras Sutcu Imam University, Biology Department) for the antimicrobial activity studies.