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Original Articles

Hydrothermal syntheses, crystal structures and antibacterial activities of two Cu(II) complexes with quinolones

, , , &
Pages 2961-2967 | Received 30 May 2007, Accepted 03 Dec 2007, Published online: 22 Sep 2010
 

Abstract

Hydrothermal reactions of ciprofloxacin with Cu(ClO4)2 · 6H2O, and ofloxacin with Cu(CH3COO)2 · 4H2O, yield two metal complexes: [Cu(H-Cip)2] · (ClO4)2 · 6H2O (1) and [Cu(Ofl)2 · H2O] · 2H2O (2), which were characterized by elemental analysis, IR and single crystal diffraction analyses. Compounds 1 and 2 were screened for antibacterial activities against Staphylococcus aureus, Escherichia coli, Candida albicans and pseudomonas aeruginosa.

Acknowledgements

This work was supported by the Doctor Foundation of Hunan University of Science and Technology (E55106).

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