Abstract
A new Zn(II) complex with 1-(1H-benzoimidazol-2-yl)-ethanone thiosemicarbazone [Zn(NO3)(H2O)(C10H11N5S)]NO3 was prepared and characterized by elemental analyses, FT-IR, 1H NMR spectroscopy, thermogravimetric analysis (TGA), X-ray diffraction (XRD), and single-crystal X-ray diffraction analysis. The coordination geometry of the pentacoordinated zinc is a distorted square pyramid. The antimicrobial activity of the complex was evaluated using a broth micro-dilution method against a panel of human pathogenic Gram positive, Gram negative bacteria and the yeast Candida albicans. The best inhibitory effect was observed against Enterobacter aerogenes (MIC = 0.031 mg mL−1).
Acknowledgements
This work was partly supported by grants from Afyonkarahisar Kocatepe University, The Presidency of the Commission of Scientific Research Projects (BAPK-042.FENED.08) and Turkish State Planning Organization (DPT-2005 K-12060). In addition, the authors acknowledge the Faculty of Arts and Sciences, Atatürk University, Erzurum, Turkey, for the use of the X-ray diffractometer purchased under grant No. 2003/219 of the University Research Fund.