Antimicrobial polyesters containing Schiff-base metal complexes

Abstract

Antimicrobial polyesters containing Schiff-base metal complexes (PSB) were prepared by polycondensation of adipoyl chloride with chelated Schiff-base diol {bis-(2-hydroxy-5-methylol-benzaldehyde)ethylenediamine}. All the metal chelated polyesters were characterized by elemental analysis, UV–Visible, FTIR, ¹³C and ¹H NMR spectra and thermogravimetric analysis. The analytical data of the polyesters agreed with 1 : 1 molar ratio (metal chelated diols to adipoyl chloride). The geometry of the chelated polyesters was confirmed by magnetic susceptibility measurements and UV–Visible spectroscopy. The thermal behaviors of these chelated polyesters were studied by TGA (Thermogravimetric analyzer) in a nitrogen atmosphere up to 800°C. The TGA results revealed that the Cu(II) chelated polyester has better heat resistant properties than the other polyesters. The antimicrobial properties of these polyesters were investigated with agar diffusion methods against selected microorganisms Bacillus subtelillis, Bacillus megaterium, Streptococcus aureus, Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa, Shigella boydii and for antifungal activity against Candida albicans, Trichophyton longifusus, Aspergillus flavus, Aspergillus niger, Fusarium solani, Microsporum canis, Puccinia graminis. The antimicrobial activity of these polyesters was higher than standard drugs Kanamycin and Miconazol.

Keywords:

• Polyester
• Schiff base
• Ethylenediamine
• Thermogravimetric analysis

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Corrigendum

Acknowledgement

The authors express their sincere thanks to “The Third World Academy of Sciences Italy” for UV, Visible spectrophotometer EZ-201 (Perkin Elmer) through research grant scheme No. 00-047 RG/CHE/AS.