Abstract
A new series of macrocyclic complexes [M(C24H28N4)X2], where M = Co(II), Ni(II), Cu(II), or Zn(II) and X = Cl−, , or CH3COO−, has been synthesized by [2+2] condensation of o-phenylenediamine with acetonylacetone (diacetonyl) in the presence of divalent metal ions. The complexes have been characterized by elemental analyses, conductance measurements, electronic, NMR, and infrared spectral studies. On the basis of these studies, a distorted octahedral geometry has been proposed for all of these complexes. The complexes were tested for in vitro antibacterial activity. Some show remarkable antibacterial activity against selected bacterial strains.
Acknowledgements
D.P. Singh thanks the University Grants Commission, New Delhi, for financial support in the form of Major Research Project. Thanks are also due to authorities of NIT Kurukshetra for providing necessary facilities. We are highly thankful to Jitender Singh for carrying out biological activities of synthesized macrocyclic complexes.