Synthesis, characterization, and antibacterial activity of yttrium(III) complexes with 2,6-pyridinedicarboxylate and pyridine

Abstract

A series of metal coordination complexes of yttrium(III) containing 2,6-pyridinedicarboxylate and pyridine have been prepared with different molar ratios of yttrium(III) to 2,6-pyridinedicarboxylate in aqueous pyridine solutions, and characterized by elemental analysis, infrared spectra, nuclear magnetic resonance, and thermal analyses. The in vitro antibacterial activities of the complexes have also been investigated against microorganisms such as Gram-negative bacteria Bacillus coli and Gram-positive bacteria Staphylococcus aureus by the disc diffusion method in DMSO. When compared to previous results, the yttrium(III) complexes of 2,6-pyridinedicarboxylate and pyridine have a moderate effect on microorganisms due to the presence of the pyridine group.

Keywords:

• Yttrium
• 2,6-Pyridinedicarboxylate
• Pyridine
• Antibacterial activity
• Coordination complex

Acknowledgments

This study was financially sponsored by Shanghai Rising-Star Program (B type) (grant no. 08QB1401500). We thank the research staff of Professor Qizhuang HE (Shanghai Normal University) for allocation of time for the antibacterial activity test.