Abstract
A new Cd(II) complex with 4′-chloro-2,2′ : 6′,2″-terpyridine (Cltpy), [Cd(Cltpy)(NO3)2(H2O)0.45(CH3OH)0.55], has been synthesized and characterized by CHN elemental analysis, 1H-NMR, 13C-NMR, IR spectroscopy, and structurally analyzed by X-ray single-crystal diffraction. The single-crystal X-ray analyses show that the coordination number is seven with three terpyridine (Cltpy) N-donors, three oxygen atoms of two nitrates and one oxygen atom of methoxy/water. The antibacterial activities of Cltpy and its Cd(II) complex are tested against different bacteria. The free ligand has considerable activity against Staphylococcus aureus, Bacillus anthracis, and Pseudomonas aeruginosa (inhibition zones ≥ 20 mm), but has moderate activity against Escherichia coli and Streptococcus pyogenes (inhibition zones ≤ 15 mm). In comparison with free Cltpy ligand, its complex has more activity against Klebsiella pneumonia, S. aureus, and B. anthracis (inhibition zones ≥ 30 mm), but is inactive against P. aeruginosa and S. pyogenes. The quantitative assays gave minimal inhibitory concentration values in the range 6.25–100 mg mL−1 that confirmed the above results. Against K. pneumonia and S. aureus, antibacterial activity of the complex is higher than Cltpy ligand.
Acknowledgments
This work was supported by the Payame Noor University, Khoy in Iran and Facultad de Quimica, Universidade de Vigo, 36310 Vigo Pontevedra in Spain.