Synthesis, structure, DNA-binding, and nuclease activity of a 3d–4f mixed metal nitrosyl complex, [Pr(phen)₂(MeOH)(H₂O)₂][Fe(CN)₅(NO)] · (Phen)(DMF)(MeOH)(H₂O)

Abstract

A cyano-bridged heterometallic lanthanide-transition metal nitrosyl complex, [Pr(phen)₂(MeOH)(H₂O)₂][Fe(CN)₅(NO)] · (Phen)(DMF)(MeOH)(H₂O) (Phen = 1,10-phenanthroline and DMF = dimethylformamide), has been synthesized from reaction of PrCl₃ · 6H₂O with 1,10-phenanthroline in methanol and sodium nitroprusside followed by crystallization from DMF. The crystal structure shows that the complex is a 1-D chain, stabilized by coordination, hydrogen-bonding, and π–π stacking interactions. The complex shows nuclease activity with pUC19 supercoiled DNA in DMF/Tris-HCl buffer in the presence of H₂O₂.

Keywords:

• 3 d–4f Heterometallic complex
• Cyanide-bridged complexes
• π–π Stacking interactions
• Metal nitrosyl compound
• Nuclease activity

Acknowledgments

The authors are grateful to Jadavpur University for providing facilities and UGC-DAE-CSR, KC (Ref.No.-CRS/09/RC03/1456), India for funding in the form of a major research project to KKM.

Notes

Contributed equally to this work.

Additional information

Notes on contributors

MD. Selim

Contributed equally to this work.