Abstract
Metal complexes [Ni(HL1)2H2O] (1) and [Fe(HL1)2] (2), where HL1 is the tridentate Schiff base N-(2-hydroxyethyl)-5-nitrosalicylaldimine, were synthesized and characterized by spectroscopic methods. The crystal structures of 1 and 2 have been determined by single crystal diffraction at 100 K. Complexes 1 and 2 have a distorted octahedral geometry. The ligand and metal complexes were screened for antibacterial and antifungal activities by the disk diffusion, microdilution broth, and single spore culture techniques. Antimicrobial activities of the ligand and its complexes have been tested against 10 bacteria, two yeast, and five filamentous fungi. The ligand and metal complexes were found to be active against all tested micro-organisms.
Acknowledgments
The financial support from the Scientific and Technical Research Council of Turkey (TUBITAK) Grant No: TBAG-108T431 and the Research Funds of Balikesir University (BAP-2010/122) is gratefully acknowledged. Dr Kara also thanks the Nato-B1-TUBITAK for funding and Prof. Guy Orpen (School of Chemistry, University of Bristol, UK) for his hospitality.