Synthesis, characterization, and crystal structure of two zinc(II) complexes with a Schiff base derived from amantadine

Abstract

By condensation of amantadine and 4-methoxysalicylaldehyde a new Schiff base HL was synthesized. A mixture of HL and zinc(II) chloride in an alcoholic medium leads to [Zn(HL)₂Cl₂] (1). However, the same reactants gave another different complex (ZnL₂) (2) in the presence of NaOH. The two complexes were characterized by IR, ¹H NMR, elemental analysis, molar conductance, and single-crystal X-ray diffraction. X-ray diffraction analysis reveals that complex 1 crystallizes in the triclinic system, Pī space group; each asymmetric unit consists of one zinc(II), two HL, and two chlorides. The tetra coordination of central zinc is attained by two chlorides and two oxygens from the Schiff base, forming a distorted tetrahedral geometry. Complex 2 crystallizes in the monoclinic system, P2₁/c space group; each asymmetric unit consists of one zinc(II) and two L. The tetra coordination of central zinc is attained by two nitrogens and two oxygens from the Schiff base, forming a distorted tetrahedral geometry.

Keywords:

• Zinc(II) complexes
• Amantadine
• Schiff base
• Synthesis
• Crystal structures

Notes

This study was financially supported by the Foundation of Liaoning Provincial Department of Education Innovation Team Projects [LT2012001]; the Cause of Public Welfare Scientific Research Fund [2012004001]; Shenyang Science and Technology Plan Project [130496]; Liaoning University Foundation of 211 Project for Innovative Talents Training and the Technology Major Projects Research Foundation [2011ZX09102–007-02], China.