Chalconoid metal chelates: spectral, biological and catalytic applications

Abstract

This review presents an outline of the spectral and biological applications of metal complexes containing chalcone and its derivatives as ligands. Chemotherapy was more or less completely based on natural products and organic compounds. However, in recent times chalcone–metal complexes have received a great deal of consideration as chemotherapeutic agents. A lot of biologically active compounds used as drugs possess modified pharmacological and toxicological potentials when administered in the form of metal-based compounds. The studies on chalcone derived transition metal complexes have been of interest because of its possible application in medicinal chemistry and catalysis. Diverse coordination environments, tunable spectral and redox properties make them valuable in many ways. Overall this review aims to provide a general overview of this emerging and rapidly expanding area of research.

Keywords:

• Modified chalcone ligands
• chalcone metal complexes
• spectral properties
• structural activity relationship
• biological activity

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

A.Yardily acknowledges University Grants Commision SERO, Hyderabad for assistance in the form of Minor Research Project. MRP-6425/16(SERO/UGC).