An antibacterial Co(II) mononuclear compound containing N,N-bis(3,5-dichlorosalicylidene)hydrazine obtained from 3,5-dichlorosalicylaldehyde thiosemicarbazone in hydrothermal conditions

Abstract

A mononuclear compound, [Co(L1)₂(H₂O)]·2H₂O (1), where L1 = N,N-bis(3,5-dichlorosalicylidene)hydrazine, was synthesized under hydrothermal conditions. Note that L1 is derived from the hydrothermal in situ reaction of L2 (L2 = 3,5-dichlorosalicylaldehyde thiosemicarbazone). L2 is prepared by reflux using 3,5-dichlorosalicylic aldehyde and thiosemicarbazide. Although 1 is only a mononuclear structure coordinated with L1, intermolecular hydrogen-bonded interactions between two adjacent mononuclear units creates a 1D supramolecular chain. Furthermore, it self-assembles into a fascinating 2D supramolecular layer via π⋅⋅⋅π stacking between benzene rings of adjacent chains. Hirshfeld surfaces and fingerprint maps of 1 were applied to obtain data on non-covalent interactions. Antibacterial analysis shows that 1 is a potential antibacterial material and the bacteriostasis rate is higher than that of L1 (E. coli: 89.41% for 1, 29.09% for L1; MRSA: 93.17% for 1, 38.54% for L1). The solid and liquid photoluminescence properties of 1 and L1 were also investigated.

Keywords:

• ,N-bis(3,5-dichlorosalicylidene)hydrazine)
• hydrothermal in situ reaction
• antibacterial activity

Disclosure statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this article.

Additional information

Funding

This work was supported by the [Natural Science Foundation of Shandong Province Foundation] under Grant [ZR2017PB006]; [Undergraduate teaching reform research project of Shandong Province] under Grant [M2022181]; [The Open Foundation of State Key Laboratory of Inorganic Synthesis and Preparative Chemistry of Jilin University] under Grant [2023-20]; and [Natural Science Foundation of Ludong University] under Grant [ld17l040].