Inherent safer design for chemical process of 1,4-dioldiacetate-2-butene oxidized by ozone

Abstract

Oxidation reaction is the typical thermal runaway reaction, and the reaction of 1, 4-dioldiacetate-2-Butene oxidized by ozone was investigated in this study. Firstly, the thermal hazards of the oxidative exothermic reactions were identified and evaluated combined process risk assessment method. The Qualitative Assessment for Inherently Safer Design (QAISD) was used to identify the risk of the reaction process. Meanwhile, the Reaction Calorimeter (RC1^e) was used to obtain the thermal properties of the oxidation reaction. Then the inherent safer designs (ISD) were proposed according to the risk assessment results to increase the level of safety of chemical industry technique. 1) ISD I: reaction temperature was improved to –5 °C, and ventilation rate was improved to 200 L•h⁻¹. 2) ISDII: using a tubular reactor as reaction vessel. The results indicated that the severity of the reaction hazard was reduced by 43%, and safety was improved significantly via two ISDs. Moreover, the inherent safety level of the reaction was increased by 63% and 43.4% via ISD Iand II, respectively. The reaction process get closer to inherent safety theories of “minimize,” “substitute,” and “moderate”.

Keywords:

• Chemical process
• Inherent safer design
• Oxidation
• Qualitative assessment
• RC1^e
• Reaction hazard

Additional information

Funding

The authors gratefully acknowledge the financial support from National Natural Science Foundation of China (21436006, 51874181), Major Program of Natural Science Foundation of Colleges and Universities of Jiangsu Province, China (17KJA620002), the Natural Science Foundation of Jiangsu Province (BK20150953) and the Priority Academic Program Development of Jiangsu Higher Education Institutions.