Prolactinoma and pregnancy – a series of cases including pituitary apoplexy

Abstract

The objective of this article is to evaluate the impact of pregnancy in women with prolactinoma, the possible consequences of therapy maintenance/discontinuation during pregnancy and to assess the type of delivery and maternal–foetal obstetrical outcome. A retrospective study of all pregnant women with prolactinoma in our Centre between 2006 and 2014 was made. We had 35 cases of pregnant women with prolactinoma, two of which had an episode of pituitary apoplexy during the second trimester. At the time of conception, most women were being treated with 5 mg bromocriptine. The majority of women had suspended medication in the 8th week of gestation. Caesarean rate was 48.6%. The maternal foetal outcome was favourable in all cases.

Key words:

• Prolactinoma
• pregnancy
• pituitary apoplexy
• caesarean section
• maternal outcome
• perinatal outcome

Disclosure statement

The authors report no declarations of interest.