Abstract
Using an immobilized acetylcholinesterase–tabun enzyme–inhibitor complex, the reactivation efficacy of a homologous series of bispyridinium reactivators with increasing length of the alkylene chain between the pyridinium rings has been studied. The number of the alkylene groups in the chain ranged from one to six. N,N′-Monomethylenebis(4-pyridiniumaldoxime) dibromide (MMB-4) and N,N′-trimethylenebis(4-pyridiniumaldoxime) dibromide (TMB-4) are the most efficient reactivators of the series.