Separation Properties of a Polymeric Octadecyl Silica Gel for Liquid Chromatography

Abstract

The synthesis of a reversed phase material, based on polymeric bonding of octadecyltrichlorosilane to 5 um silica gel, is described. This phase, which exhibits unique properties with respect to the separation of polynuclear aromatic hydrocarbons (PAH), was tested and evaluated both in an analytical and an upscaled analytical mode. Effects of use of the phase over a long period of time are demonstrated and the material is characterized by surface coverage, resolution of critical isomers and separation capacity for a mixture of PAHs.