Thin Layer Chromatographic Method for the Determination of Surfadone^TM QSP in Formulated Products

Abstract

Thin layer chromatography with densitometric detection is utilized for the quantitative analysis of Surfadone^TM QSP in formulated products. Iodoplatinate reagent is used to derivatize the quaternary ammonium surfactant, yielding a colored species with a maximum absorbance at 525 nm. The high polarity of the surfactant is demonstrated by comparison of its chromatographic behavior to that of other commercially available materials. Prototype formulations (foaming conditioner, styling glaze) were analyzed yielding excellent accuracy and precision.