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Original Articles

Structural Factors Affecting Chiral Recognition and Separation on Cellulose Based Chiral Stationary Phases

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Pages 485-492 | Published online: 23 Oct 2006
 

Abstract

The structural factors and functional group selectivity requirements affecting direct high-performance liquid chromatographic enantiomeric resolution of drug racemates on several derivatized cellulose chiral stationary phases are reviewed.

A guide for the choice of the appropriate chiral cellulose derivative column based on elements of asymmetry and functional groups of the compounds are presented.

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