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Theory and Methods

New Estimands for Experiments with Strong Interference

Received 02 Jul 2021, Accepted 22 Sep 2023, Published online: 11 Dec 2023
 

Abstract

In experiments that study social phenomena, such as peer influence or herd immunity, the treatment of one unit may influence the outcomes of others. Such “interference between units” violates traditional approaches for causal inference, so that additional assumptions are often imposed to model or limit the underlying social mechanism. For binary outcomes, we propose new estimands that can be estimated without such assumptions, allowing for interval estimates that assume only the randomization of treatment. However, the causal implications of these estimands are more limited than those attainable under stronger assumptions. The estimand shows whether the treatment effects under the observed assignment varied systematically as a function of each unit’s direct and indirect exposure to treatment, while also lower bounding the number of units affected. Supplementary materials for this article are available online.

Supplementary Materials

The supplement contains additional data examples; proof of (10) and (25); asymptotic results regarding consistency and interval coverage for regression estimands (including Proposition 1); and data summaries.

Acknowledgments

The author wishes to acknowledge helpful discussions with Brian Kovak, Dan Nagin, Beka Steorts, Eric Tchetgen Tchetgen, and Stefan Wager, as well as detailed and insightful feedback from the editors and reviewers

Disclosure Statement

The author reports there are no competing interests to declare.

Notes

1 In the terminology of Imbens and Manski (Citation2004), σθ2 has identification set [0, 1/4], inducing an identification set for the prediction interval of τ̂1τ1.

2 Under conditions where τ̂1 is consistent for τ1, such as those of Proposition 1, assumptions that imply consistency of τ^1 for the EATE also imply convergence of τ1 to the EATE.

3 To see this, consider that if Y is deterministic, then Eτ̂1=0 and a confidence interval for Eτ̂1 is given by τ̂1±z1αNN1NN1N0 σY2, where σY2 is the variance of Y1,,YN. As σY2 is upper bounded by 1/4, this interval is contained by the prediction interval of Proposition 1.

4 As UwTθL holds with probability 1α, adding wTY implies wTYUwTAwTYL holds with the same probability.

6 Available in the R package inferference.

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