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Original Articles

Low Plasma Omega-3 Fatty Acid Levels May Predict Inferior Prognosis in Untreated Diffuse Large B-Cell Lymphoma: A New Modifiable Dietary Biomarker?

, , , , , , & show all
Pages 1088-1090 | Received 26 Mar 2017, Accepted 01 Jul 2018, Published online: 20 Sep 2018
 

Abstract

Dietary factors that may reduce the risk of relapse or prolong remission are an area of interest for patients with cancer. There is little data on the role of omega-3 fatty acids (n-3 FA) in patients diagnosed with lymphoma. This pilot biomarker study evaluated the prognostic significance of n-3 FA levels in patients with diffuse large B-cell lymphoma (DLBCL). In this analysis, low n-3 FA may be associated with inferior event free survival at 24 months in this disease. Larger studies are needed to confirm this association and could provide the basis for prospective investigation of whether modifying n-3 levels with diet may improve outcome in lymphoma.

Disclosure Statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This research was supported by the Mayo Clinic/University of Iowa Lymphoma SPORE grant from the National Institute of Health (P50 CA97274-13) and the Predolin Foundation.

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