The Relationship Between Vitamin D Status and Risk of Gastric Cancer

Abstract

Vitamin D plays an important role in the metabolism of calcium and phosphorus and bone health, but is also involved in several other important biological processes. Epidemiological studies indicate that the prevalence of vitamin D deficiency is very high globally. Recent studies have shown an association between vitamin D status with the prevalence and outcomes of several cancers that includes gastric cancer, which is a common cancer with a poor prognosis. The early diagnosis and treatment of gastric cancer, in its advanced stages, is difficult and patients who are diagnosed at an advanced stage have a poor prognosis. In this review, we have summarized the recent studies investigating the association between vitamin D status and the incidence and mortality of gastric cancer.

Disclosure Statement

The authors have no conflict of interest to disclose.

Additional information

Funding

This study was supported by a grant from Mashhad University of Medical Sciences.

Notes on contributors

Seyed Mostafa Parizadeh

All the authors listed above fulfilled the authorship criteria but some of them has more focus on the listed items. Seyed Mostafa Parizadeh, Reza Jafarzadeh-Esfehani, and Maryam Ghandehari have contributions in acquisition and interpretation of data as well as drafting the article. Dr. Seyyed Mostafa Parizadeh and Dr. Amir Avan have contributions in designing the review as well as acquisition and interpretation of data as well as drafting the article. Dr. Reza Jafarzadeh Esfehani and Seyed Mahdi Hassanian and Majid Ghayour-Mobarhan and Gordon A. Ferns and Amir Avan have contributions in conception and design acquisition of data as well as performing critical revising for important intellectual content. All the listed authors approved the final version of manuscript.

Maryam Ghandehari

All the authors listed above fulfilled the authorship criteria but some of them has more focus on the listed items. Seyed Mostafa Parizadeh, Reza Jafarzadeh-Esfehani, and Maryam Ghandehari have contributions in acquisition and interpretation of data as well as drafting the article. Dr. Seyyed Mostafa Parizadeh and Dr. Amir Avan have contributions in designing the review as well as acquisition and interpretation of data as well as drafting the article. Dr. Reza Jafarzadeh Esfehani and Seyed Mahdi Hassanian and Majid Ghayour-Mobarhan and Gordon A. Ferns and Amir Avan have contributions in conception and design acquisition of data as well as performing critical revising for important intellectual content. All the listed authors approved the final version of manuscript.

Reza Jafarzadeh-Esfehani

All the authors listed above fulfilled the authorship criteria but some of them has more focus on the listed items. Seyed Mostafa Parizadeh, Reza Jafarzadeh-Esfehani, and Maryam Ghandehari have contributions in acquisition and interpretation of data as well as drafting the article. Dr. Seyyed Mostafa Parizadeh and Dr. Amir Avan have contributions in designing the review as well as acquisition and interpretation of data as well as drafting the article. Dr. Reza Jafarzadeh Esfehani and Seyed Mahdi Hassanian and Majid Ghayour-Mobarhan and Gordon A. Ferns and Amir Avan have contributions in conception and design acquisition of data as well as performing critical revising for important intellectual content. All the listed authors approved the final version of manuscript.

Seyed Mohammadreza Parizadeh

All the authors listed above fulfilled the authorship criteria but some of them has more focus on the listed items. Seyed Mostafa Parizadeh, Reza Jafarzadeh-Esfehani, and Maryam Ghandehari have contributions in acquisition and interpretation of data as well as drafting the article. Dr. Seyyed Mostafa Parizadeh and Dr. Amir Avan have contributions in designing the review as well as acquisition and interpretation of data as well as drafting the article. Dr. Reza Jafarzadeh Esfehani and Seyed Mahdi Hassanian and Majid Ghayour-Mobarhan and Gordon A. Ferns and Amir Avan have contributions in conception and design acquisition of data as well as performing critical revising for important intellectual content. All the listed authors approved the final version of manuscript.

Seyed Mahdi Hassanian

All the authors listed above fulfilled the authorship criteria but some of them has more focus on the listed items. Seyed Mostafa Parizadeh, Reza Jafarzadeh-Esfehani, and Maryam Ghandehari have contributions in acquisition and interpretation of data as well as drafting the article. Dr. Seyyed Mostafa Parizadeh and Dr. Amir Avan have contributions in designing the review as well as acquisition and interpretation of data as well as drafting the article. Dr. Reza Jafarzadeh Esfehani and Seyed Mahdi Hassanian and Majid Ghayour-Mobarhan and Gordon A. Ferns and Amir Avan have contributions in conception and design acquisition of data as well as performing critical revising for important intellectual content. All the listed authors approved the final version of manuscript.

Majid Ghayour-Mobarhan

All the authors listed above fulfilled the authorship criteria but some of them has more focus on the listed items. Seyed Mostafa Parizadeh, Reza Jafarzadeh-Esfehani, and Maryam Ghandehari have contributions in acquisition and interpretation of data as well as drafting the article. Dr. Seyyed Mostafa Parizadeh and Dr. Amir Avan have contributions in designing the review as well as acquisition and interpretation of data as well as drafting the article. Dr. Reza Jafarzadeh Esfehani and Seyed Mahdi Hassanian and Majid Ghayour-Mobarhan and Gordon A. Ferns and Amir Avan have contributions in conception and design acquisition of data as well as performing critical revising for important intellectual content. All the listed authors approved the final version of manuscript.

Gordon A. Ferns

All the authors listed above fulfilled the authorship criteria but some of them has more focus on the listed items. Seyed Mostafa Parizadeh, Reza Jafarzadeh-Esfehani, and Maryam Ghandehari have contributions in acquisition and interpretation of data as well as drafting the article. Dr. Seyyed Mostafa Parizadeh and Dr. Amir Avan have contributions in designing the review as well as acquisition and interpretation of data as well as drafting the article. Dr. Reza Jafarzadeh Esfehani and Seyed Mahdi Hassanian and Majid Ghayour-Mobarhan and Gordon A. Ferns and Amir Avan have contributions in conception and design acquisition of data as well as performing critical revising for important intellectual content. All the listed authors approved the final version of manuscript.

Amir Avan

All the authors listed above fulfilled the authorship criteria but some of them has more focus on the listed items. Seyed Mostafa Parizadeh, Reza Jafarzadeh-Esfehani, and Maryam Ghandehari have contributions in acquisition and interpretation of data as well as drafting the article. Dr. Seyyed Mostafa Parizadeh and Dr. Amir Avan have contributions in designing the review as well as acquisition and interpretation of data as well as drafting the article. Dr. Reza Jafarzadeh Esfehani and Seyed Mahdi Hassanian and Majid Ghayour-Mobarhan and Gordon A. Ferns and Amir Avan have contributions in conception and design acquisition of data as well as performing critical revising for important intellectual content. All the listed authors approved the final version of manuscript.