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Articles

Cancer-Related Fatigue, Laboratory Markers as Indicators for Nutritional Status among Patients with Colorectal Cancer

Pages 903-908 | Received 09 Jul 2019, Accepted 15 Sep 2019, Published online: 01 Oct 2019
 

Abstract

Our objective was to determine the relationship between cancer-related fatigue (CRF), laboratory markers, and nutritional status among patients with colorectal cancer (CRC). A cross-sectional design was used. A sample of 80 participants diagnosed with CRC participated and completed the study's surveys including the patient-generated subjective global assessment (PG-SGA), cancer fatigue scale (CFS), laboratory markers sheet, and patient-related factors sheet. Positive relationships were identified between PG-SGA and CRF, physical fatigue, cognitive fatigue, WBC, and calcium level (r = 0.781, 0.820, 0.751, 0.680, and 0.710; P = 0.001 respectively). Negative relationships were found between PG-SGA and sodium, potassium, and hemoglobin levels (r = −0.801, −0.761, and −0.810; P = 0.001 respectively). The regression analysis revealed an R2 = 0.610 (adjusted R2 = 0.590), F (4.58, P < 0.001). Finally, the above-mentioned independent variables accounted for 61.0% of the variance in PG-SGA. Patients with CRC are experiencing nutritional problems during their treatment. Cancer-related fatigue and other laboratory markers are considered indicators for nutritional status. Clinical dietitians and oncology nurses can work together to monitor these parameters and provide clinical treatment when needed.

Acknowledgment

The author would like to thank the participants for their effort and time.

Disclosure Statement

The author declares that they have no conflict of interest.

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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