Abstract
The incidence of short-term complications after laparoscopic surgery for gastric cancer is higher. Whether ω-3 fish oil fat emulsion can reduce short-term complications of gastric cancer after laparoscopic surgery is controversial. The purpose of this study was to explore the effect of ω-3 fish oil fat emulsion on postoperative recovery of patients with gastric cancer after laparoscopic surgery. A total of 111 patients were included in this study. These patients were given parenteral nutrition for 5 day or more after surgery. We used univariate analysis and multivariate analysis to determine whether ω-3 fish oil fat emulsion could affect the incidence of short-term complications after gastric cancer laparoscopic surgery. The incidence of postoperative short-term complications in patients with parenteral nutrition supplemented with ω-3 fish oil fat emulsion was significantly lower than that in patients without ω-3 fish oil fat emulsion (12/51 VS 26/60, P = 0.027). ω-3 fish oil fat emulsion is an independent risk factor for short-term postoperative complications in patients with gastric cancer (OR = 0.393, CI:0.155-0.996, P = 0.049). In conclusion, the addition of ω-3 fish oil fat emulsion to parenteral nutrition after operation can effectively reduce the incidence of short-term complications in patients with gastric cancer after laparoscopic surgery.
Acknowledgments
The authors thank all of the investigators for their contributions to the study.
Disclosure Statement
There are no competing interests.
Author Contributions
Zhijian Liu, Li Chen and Xiaofeng Lu contributed to study conception and design, Zhijian Liu and Xiaolong Ge contributed to drafting of manuscript, Bingxin Lv, Zhijian Liu, and Feng Sun contributed to acquisition of data, Feng Sun, Shichao Ai and Xing Kang contributed to analysis and interpretation of data, Xiaofeng Lu and Xiaolong Ge contributed to critical revision.