https://orcid.org/0000-0002-6627-6179
![Sample our Health and Social Care journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/5938/TOC-Subject-Sample-2021-Health-Social-Care.jpg"})
Abstract
There are conflicting data with regards to the link between diet and the prostate cancer. The purpose of this study was to assess the association of dietary factors with incidence, prevalence and mortality rates of prostate cancer worldwide. We conducted an ecological study including 170 countries, whose data on incidence, prevalence and mortality rates of prostate cancer, dietary factors, and potentially confounding factors were available and collected in May 2020. Univariable and multivariable linear regression analyses were used. Consumption of nuts and seeds was inversely associated with incidence, prevalence and mortality rates of prostate cancer (β −0.7, P < 0.001; β −2.1, P < 0.001; β −0.1, P = 0.02; respectively). Intake of alcohol was associated with increased incidence, prevalence and mortality rates of prostate cancer (β 1.8, P < 0.001; β 4.5, P < 0.001; β 0.4, P < 0.001; respectively). Consumption of processed meats was also associated with increased incidence and prevalence rates of prostate cancer (β 0.6, P = 0.003; β 2.8, P = 0.001; respectively). These data suggest that consumption of nuts and seeds have a protective effect against prostate carcinogenesis, progression, and metastasis, while alcohol and processed meat increase these risks.
Ethics Approval and Consent to Participate
Not applicable.
Consent for Publication
Not applicable.
Availability of Data and Materials
All data generated or analyzed during this study are included in this published article and its supplementary file 1.
Supplementary File
File name: supplementary file one
File format: .xls
Title of data: Collected data
Description of data: age-standardized incidence, prevalence, and mortality rates of prostate cancer, dietary factors, prevalence of obesity, prevalence of insufficient physical activity, and human development index.
Acknowledgments
Not applicable.
Disclosure Statement
The authors declare that they have no competing interests.
Funding
None.
Authors’ Contributions
All authors were involved in the design of the study. IZ collected the data. IZ performed the analysis, with support from LL. IZ wrote the first draft of the manuscript, with support from AMT and YN. YN, SS, FS, FA and YK critically reviewed the manuscript. All the authors have read and approved the final version.