Lack of Relationship between Central Corneal Thickness and Papilloedema in Idiopathic Intracranial Hypertension

ABSTRACT

Translaminar pressure gradient abnormalities have been implicated in the pathogenesis and progression of glaucoma. A “reversed” translaminar pressure gradient may be related to papilloedema severity in idiopathic intracranial hypertension. Central corneal thickness is related to intraocular pressure measurements and, by extension, to translaminar pressure gradients. We evaluated if central corneal thickness could be a marker of worse papilloedema due to altered translaminar pressure gradients in patients with idiopathic intracranial hypertension. We found that central corneal thickness was not related to the severity of papilloedema in idiopathic intracranial hypertension.

KEYWORDS:

• Central corneal thickness
• translaminar pressure gradient
• idiopathic intracranial hypertension
• glaucoma

Declaration of interest

The authors report no conflicts of interest.

Additional information

Funding

This work was supported in part by an unrestricted departmental grant (Department of Ophthalmology) from Research to Prevent Blindness, Inc., New York; and by NIH/National Eye Institute [P30-EY06360].