Corticosteroid Withdrawal after Complete Resection of Recurrent IgG4-Related Ophthalmic Disease

ABSTRACT

Corticosteroids are the first-line treatment for immunoglobulin G4-related ophthalmic disease (IgG4-ROD). However, the therapeutic effect of corticosteroids is unpredictable, and recurrences occur frequently. We present a case of a 60-year-old woman with IgG4-ROD of the lacrimal fossa. She was first treated with oral prednisolone, which was tapered within three months. However, proptosis recurred two months after prednisolone withdrawal. En bloc excision of the lesion was performed via the eyelid crease approach. The patient is lesion-free without corticosteroids at 18 months after surgery. Complete resection can be a powerful strategy for IgG4-ROD if a well-defined lesion is located in accessible areas.

KEYWORDS:

• Complete resection
• corticosteroid
• IgG4-related ophthalmic disease
• recurrent lesion

Acknowledgements

We would like to thank Editage [http://www.editage.com] for editing and reviewing this manuscript for the English language.

Declaration of interest statement

The authors report no conflict of interest.

Additional information

Funding

The authors received no financial support for the research, authorship, and/or publication of this article.