ABSTRACT
In order to review the clinical features of anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis (MOGON), we investigated the clinical characteristics, visual function, optical coherence tomography findings, and magnetic resonance imaging of 31 patients (44 eyes). MOGON was more common in middle age without sex difference and was characterised by pain on eye movement and optic disc swelling. Magnetic resonance imaging lesions tended to be long with inflammation around the optic nerve sheath; longer lesions were associated with worse visual acuities at onset. Recurrence was significantly associated with retinal nerve fibre layer thinning, and thus, it is important to reduce recurrence as much as possible.
Disclosure statement
Toshiyuki, T received research grants from Cosmic Corporation Co Ltd. and Medical & Biological Laboratories CO Ltd.
Data availability statement
All data generated or analysed during this study are included in this article. Further enquiries can be directed to the corresponding author.
Statement of ethics
The research has been complied with all the relevant national regulations, and institutional policies and in accordance with the tenets of the Helsinki Declaration and has been approved by the Inouye Eye Hospital’s institutional review board (202307–5). Informed consent was obtained as an opt-out on the website, allowing the participants to refuse participation in the study at any time.