Obstructive Sleep Apnea in Idiopathic Intracranial Hypertension: Systematic Review and Meta-Analysis

ABSTRACT

This study aims to determine the association between obstructive sleep apnea (OSA) and idiopathic intracranial hypertension (IIH). A systematic review and meta-analysis were performed per the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. A search of electronic information through MEDLINE, EMBASE, and Cochrane Library was conducted to identify all studies reporting the association between OSA and IIH. The primary outcome was the prevalence of OSA. A random effects model was used for the analysis. Of 1469 studies identified, eight studies enrolling 241 patients were included. Overall, the pooled estimate of the proportion of OSA in patients with IIH was 0.424 (95% CI: 0.258 to 0.609), indicating a significant association (p < .05). In subgroup analysis, individuals with confirmed OSA diagnosis exhibited a prevalence rate of 0.407 (CI: 0.235 to 0.604, p < .05). For those with a positive OSA screening, the prevalence rate was 0.464 (CI: 0.043 to 0.943, p < .05). Clinicians should screen for OSA in patients with newly diagnosed IIH.

KEYWORDS:

• Obstructive sleep apnea
• idiopathic intracranial hypertension
• prevalence
• screening
• diagnosis

Disclosure statement

No potential conflict of interest was reported by the author(s).

Data availability statement

The datasets generated and analysed during the current study are available from the corresponding author on reasonable request.

Additional information

Funding

The author(s) reported there is no funding associated with the work featured in this article.