Lacrimal drainage system anomalies in Williams-Beuren syndrome

ABSTRACT

Williams-Beuren syndrome is a rare multi-system disorder affecting 1:10000 to 1:20000 live-births. The cause is de novo contiguous gene deletion on the long arm of chromosome 7 (7q11.23). It typically manifests with dysmorphic facies and predominantly involves the connective tissues, cardiovascular and nervous systems. The published literature reveals that lacrimal drainage anomalies are exceptionally rare and not much is known of those reported. The present case describes multiple lacrimal drainage anomalies in a child with Williams-Beuren syndrome.

KEYWORDS:

• Anomalies
• CNLDO
• epiphora
• lacrimal
• nasolacrimal duct
• Williams-Beuren syndrome
• Williams syndrome

Disclosure statement

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.

Financial disclosure

Mohammad Javed Ali receives royalties from Springer for his treatises “Principles and Practice of Lacrimal Surgery” and ‘Atlas of Lacrimal Drainage Disorders’.