Bilateral orbital inflammation in a 6-month old with SARS-CoV-2 infection

ABSTRACT

A 6-month-old female presented with bilateral periorbital edema for 7 days. Laboratory testing was significant for active SARS-CoV-2 infection. Neuroimaging demonstrated soft tissue changes within the bilateral orbits and enlargement of the bilateral lacrimal glands. Although the patient initially improved with corticosteroid treatment, she later returned with recurrent left periorbital and eyelid edema. Orbital biopsy was performed and demonstrated findings in the lacrimal gland and the adjacent fibroconnective tissues that are similar to those of prior lung specimens seen in SARS-CoV-2 patients. Final diagnosis was bilateral orbital inflammation with features presumed secondary to SARS-CoV-2 infection. To the best of our knowledge, this is one of the first reports to document bilateral orbital inflammation as a sign of SARS-CoV-2 infection in the pediatric population with the associated pathological findings.

KEYWORDS:

• Orbital inflammation
• orbitotomy
• pediatrics
• SARS-CoV-2

Disclosure statement

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.

Ethics statement

All research was performed ethically and follows the principles of the Declaration of Helsinki.