Acellular cadaveric dermal matrix grafts for orbital wall reconstruction in patients with sinonasal malignancies

ABSTRACT

Purpose

To describe the utilization of acellular cadaveric dermal matrix (ACDM) in patients undergoing orbital wall reconstruction after orbital preservation surgery for sinonasal malignancy.

Methods

Retrospective case series of seven patients with sinonasal malignancy who had orbital reconstruction with ACDM implants from January 2012 to August 2020. Orbital preservation was performed in all patients with tumor extension up to and including periorbital. The main outcome measures were implant exposure, orbital infection, diplopia in primary gaze, enophthalmos, and eyelid malposition.

Results

Patients ranged 37–78 years old (median: 66 years) and included 4 females and 3 males. The median follow-up time was 9 months (range 6–43 months) from the date of surgery. Squamous cell carcinoma comprised the majority of tumors with all patients needing medial wall reconstruction. Three patients received postoperative radiation therapy. No patients had any implant exposure, orbital infection, enophthalmos, or eyelid malposition.

Conclusions

ACDM grafts can be used safely in orbital wall reconstruction in patients with sinonasal malignancies.

KEYWORDS:

• Acellular cadaveric dermal matrix (ACDM)
• alloplastic implants
• orbital wall reconstruction
• sinonasal malignancy

Meeting presentation

ASOPRS 51st Fall Scientific Symposium, November 22, 2020; Awarded the 2020 Bartley Frueh, MD Award for Best YASOPRS Presentation.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Proprietary interest statement

Authors have no relevant financial relationships to disclose

Additional information

Funding

This research was supported by funding from P30 EY010572 (NEI Core grant to OHSU)and an unrestricted grant from Research to Prevent Blindness. The sponsors did not have any role in study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the manuscript for publication.